Document Detail

Maternal neonatal outcome in quadruplet and quintuplet versus triplet gestations.
MedLine Citation:
PMID:  10690673     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Examination and comparison of the natural histories of triplet versus quadruplet and quintuplet gestations. STUDY DESIGN: A retrospective study of sixty-four multifetal pregnancies (fifty-two sets of triplets, nine sets of quadruplets and three sets of quintuplets) cared for during past 12 years in our department. Quintuplets and quadruplets were compared with triplet pregnancies according to gestational age, birthweight, pregnancy complications and perinatal outcome. Student's t-test, Fisher exact test and chi2 test were used for statistical analysis, considering P value of <0.05 as statistically significant. RESULTS: Although mean gestational age at delivery between triplets and higher order gestations was not significantly different, birthweight of quadruplets and quintuplets was significantly lower. Pregnancy complications, including intrauterine growth retardation, were equally distributed between the groups. Early neonatal and perinatal mortality were significantly higher in quadruplets and quintuplets than in triplets. Surprisingly, survival of growth retarded fetuses was better than survival of their eutrophic counterparts. The spontaneous loss rate was 11.5% for entire triplet gestation and 16.7% for quadru- and quintuplet pregnancies. CONCLUSIONS: As the spontaneous loss rate of triplets and higher order pregnancies observed in our study is quite similar to pregnancy loss rate caused by multifetal pregnancy reduction, conservative management of multifetal pregnancies in specialised tertiary centers seems to be a prudent solution.
S Skrablin; I Kuvacić; D Pavicić; D Kalafatić; T Goluza
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  88     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  2000 Feb 
Date Detail:
Created Date:  2000-03-10     Completed Date:  2000-03-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  147-52     Citation Subset:  IM    
Department of Perinatal Medicine, University Medical School, Zagreb, Croatia.
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MeSH Terms
Birth Weight
Cervix Uteri / surgery
Fetal Growth Retardation / epidemiology
Fetal Membranes, Premature Rupture / epidemiology
Gestational Age
Infant Mortality
Infant, Newborn
Infant, Premature
Obstetric Labor, Premature / epidemiology
Pre-Eclampsia / epidemiology
Pregnancy Complications / epidemiology
Pregnancy Outcome*
Pregnancy, Multiple*
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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