| Maternal and neonatal morbidities associated with obstructive sleep apnea complicating pregnancy. | |
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MedLine Citation:
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PMID: 20005507 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of the study was to estimate the maternal and neonatal morbidities associated with obstructive sleep apnea (OSA) in pregnancy. STUDY DESIGN: Women delivering between 2000-2008 with confirmed OSA in an academic center were included. Normal-weight and obese controls were randomly selected at a 2:1 ratio. Maternal and neonatal morbidities were compared between the groups. Multivariate analyses were performed to evaluate maternal morbidity and preterm birth (PTB). RESULTS: The analysis included 57 pregnancies complicated by OSA. Compared with normal-weight (n = 114) controls, OSA patients had more preeclampsia (PET) (19.3% vs 7.0%; P = .02) and PTB (29.8% vs 12.3%; P = .007). Controlling for comorbid conditions, OSA was associated with an increased risk of PTB (odds ratio [OR], 2.6; 95% confidence interval [CI], 1.02-6.6), mostly secondary to PET (63%). Cesarean delivery (OR, 8.1; 95% CI, 2.9-22.1) and OSA were associated with maternal morbidity (OR, 4.6; 95% CI, 1.5-13.7). CONCLUSION: Pregnancies complicated by OSA are at increased risk for preeclampsia, medical complications, and indicated PTB. |
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Authors:
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Judette M Louis; Dennis Auckley; Robert J Sokol; Brian M Mercer |
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Publication Detail:
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Type: Journal Article Date: 2009-12-14 |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 202 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-03-08 Completed Date: 2010-04-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 261.e1-5 Citation Subset: AIM; IM |
Copyright Information:
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Copyright 2010 Mosby, Inc. All rights reserved. |
Affiliation:
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Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Case Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, OH, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Case-Control Studies Cesarean Section / statistics & numerical data Cohort Studies Diabetes Mellitus / epidemiology Female Humans Multivariate Analysis Obesity / epidemiology Pre-Eclampsia / epidemiology* Pregnancy Pregnancy Complications / epidemiology* Premature Birth / epidemiology* Retrospective Studies Sleep Apnea, Obstructive / epidemiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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