Document Detail

Maternal and neonatal effects of single-dose epidural anesthesia with lidocaine and morphine for cesarean delivery.
MedLine Citation:
PMID:  9529839     Owner:  NLM     Status:  MEDLINE    
Two per cent lidocaine (18-20 ml) with epinephrine 1:200,000 plus 4 mg of morphine was given as a single epidural injection over 3 minutes for elective cesarean section in 60 healthy mothers at term. It provided effective, safe and adequate analgesia in the postoperative period. There was no evidence of neonatal depression related to the epidural morphine as judged by Apgar scores at 1 and 5 minutes and umbilical venous pH at birth. Maternal and umbilical venous levels of morphine were measured and found to be low at birth. However, this study was done only in healthy mothers not in labor and having a term fetus. We do not recommend using this technique in complicated obstetric patients.
S Niruthisard; W Somboonviboon; P Thaithumyanon; N Mahutchawaroj; A Chaiyakul
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Publication Detail:
Type:  Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  81     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-04-23     Completed Date:  1998-04-23     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  103-9     Citation Subset:  IM    
Department of Anesthesiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
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MeSH Terms
Analgesics, Opioid / administration & dosage*
Anesthesia, Epidural / methods*
Anesthesia, Obstetrical / methods*
Anesthetics, Local / administration & dosage*
Apgar Score
Cesarean Section*
Dose-Response Relationship, Drug
Fetal Blood / chemistry
Infant, Newborn
Lidocaine / administration & dosage*
Morphine / administration & dosage*
Pain Measurement
Pain, Postoperative / physiopathology
Pregnancy Outcome*
Regression Analysis
Reg. No./Substance:
0/Analgesics, Opioid; 0/Anesthetics, Local; 137-58-6/Lidocaine; 57-27-2/Morphine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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