| Maternal and neonatal effects of single-dose epidural anesthesia with lidocaine and morphine for cesarean delivery. | |
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MedLine Citation:
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PMID: 9529839 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two per cent lidocaine (18-20 ml) with epinephrine 1:200,000 plus 4 mg of morphine was given as a single epidural injection over 3 minutes for elective cesarean section in 60 healthy mothers at term. It provided effective, safe and adequate analgesia in the postoperative period. There was no evidence of neonatal depression related to the epidural morphine as judged by Apgar scores at 1 and 5 minutes and umbilical venous pH at birth. Maternal and umbilical venous levels of morphine were measured and found to be low at birth. However, this study was done only in healthy mothers not in labor and having a term fetus. We do not recommend using this technique in complicated obstetric patients. |
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Authors:
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S Niruthisard; W Somboonviboon; P Thaithumyanon; N Mahutchawaroj; A Chaiyakul |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of the Medical Association of Thailand = Chotmaihet thangphaet Volume: 81 ISSN: 0125-2208 ISO Abbreviation: J Med Assoc Thai Publication Date: 1998 Feb |
Date Detail:
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Created Date: 1998-04-23 Completed Date: 1998-04-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7507216 Medline TA: J Med Assoc Thai Country: THAILAND |
Other Details:
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Languages: eng Pagination: 103-9 Citation Subset: IM |
Affiliation:
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Department of Anesthesiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Analgesics, Opioid / administration & dosage* Anesthesia, Epidural / methods* Anesthesia, Obstetrical / methods* Anesthetics, Local / administration & dosage* Apgar Score Cesarean Section* Dose-Response Relationship, Drug Female Fetal Blood / chemistry Humans Infant, Newborn Lidocaine / administration & dosage* Morphine / administration & dosage* Pain Measurement Pain, Postoperative / physiopathology Pregnancy Pregnancy Outcome* Regression Analysis |
| Chemical | |
Reg. No./Substance:
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0/Analgesics, Opioid; 0/Anesthetics, Local; 137-58-6/Lidocaine; 57-27-2/Morphine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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