Document Detail


Maternal mercury exposure and neuro-motor development in breastfed infants from Porto Velho (Amazon), Brazil.
MedLine Citation:
PMID:  17011234     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fish is an important item in the diet of Amazonians, and per se is their best single source of essential nutrients. Rapid urbanization and migration are bringing changes in dietary habits of Amazonians. Exposure to fish-Hg during pregnancy and lactation were studied in 100 women and newborns from Porto Velho. Tissue-Hg concentrations and neurodevelopment (Gesell Developmental Schedules) were assessed at birth and at 6 months in exclusively breastfed infants. Maternal mean frequency of fish consumption was low (<2 meals/week; range 0->7 meals/week) compared to Amazonian standards. Women consuming <2 fish meals/week showed less median hair-Hg (3.5 microgg-1) than women that consumed 2 fish meals/week (5.7 microgg). Median total Hg in maternal hair (5.4 microgg-1) was higher than in newborns (1.6 microgg-1). Significant correlation was observed between maternal hair-Hg and infant hair-Hg at birth (r=0.353; p<0.01) and at six months (r=0.510; p<0.01). Placenta-Hg was also significantly correlated to maternal hair-Hg (r=0.321; p<0.01), newborn hair-Hg (r=0.219; p<0.05), maternal blood-Hg (r=0.250; p<0.01) and to umbilical cord-Hg (r=0.857; p<0.01). Most infants (74%) had normal Gesell Schedules but among the 26% showing neuro-motor development delays only six (7%) had multiple (motor, language, and adaptative) delays. The infants with multiple delays were born from mothers with range of hair-Hg comparable to mothers of normally developed infants. Coincidentally, mothers of infants with multiple delays also showed the lowest range of income and level of education. Fish consumption, income, and level of education varied greatly among these breastfeeding urban mothers. It seems that development delays of exclusively breastfed infants are a component of the health inequalities that accompanies socioeconomic disadvantages.
Authors:
Rejane Corrêa Marques; José Garrofe Dórea; Wanderley Rodrigues Bastos; Mauro de Freitas Rebelo; Márlon de Freitas Fonseca; Olaf Malm
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-09-29
Journal Detail:
Title:  International journal of hygiene and environmental health     Volume:  210     ISSN:  1438-4639     ISO Abbreviation:  Int J Hyg Environ Health     Publication Date:  2007 Jan 
Date Detail:
Created Date:  2007-01-22     Completed Date:  2007-04-05     Revised Date:  2007-06-21    
Medline Journal Info:
Nlm Unique ID:  100898843     Medline TA:  Int J Hyg Environ Health     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  51-60     Citation Subset:  IM    
Affiliation:
Fundação Universidade Federal de Rondônia, Porto Velho, RO, Brazil. rejanecmarques@globo.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Animals
Brazil
Breast Feeding*
Environmental Monitoring
Female
Fishes
Food Contamination*
Hair / chemistry
Humans
Infant
Infant, Newborn
Language Development
Maternal Exposure / adverse effects*
Mercury / analysis,  blood,  toxicity*
Motor Skills / drug effects
Placenta / chemistry
Pregnancy
Umbilical Cord / chemistry
Water Pollutants, Chemical / analysis,  blood,  toxicity*
Chemical
Reg. No./Substance:
0/Water Pollutants, Chemical; 7439-97-6/Mercury

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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