Document Detail


Maternal immunization with inactivated influenza vaccine: rationale and experience.
MedLine Citation:
PMID:  12850360     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Inactivated influenza vaccine is recommended for routine use in high-risk individuals in the United States, including women who will be in the second or third trimesters of pregnancy. The basis for this recommendation is the high risk of exposure and disease due to influenza viruses in pregnant women, as well as the impact of influenza virus infection on the fetus and infant. Historical data from the influenza pandemics of 1918 and 1957 illustrate the potential risks of this infection in pregnant women and their fetuses. Prospective studies have demonstrated higher cord antibody levels to influenza in babies born to mothers immunized during pregnancy, and a delay in the onset and decrease in severity of babies born with higher antibody levels. Increased influenza vaccine use during pregnancy has the potential to benefit both the woman and her infant.
Authors:
Janet A Englund
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Vaccine     Volume:  21     ISSN:  0264-410X     ISO Abbreviation:  Vaccine     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-07-09     Completed Date:  2003-08-20     Revised Date:  2005-11-22    
Medline Journal Info:
Nlm Unique ID:  8406899     Medline TA:  Vaccine     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  3460-4     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE # 8G, Seattle, WA 98105, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fetus / physiology
Humans
Infant, Newborn
Influenza Vaccines / immunology*
Influenza, Human / physiopathology
Maternal-Fetal Exchange
Pregnancy
Pregnancy Complications, Infectious / physiopathology
Vaccines, Inactivated / immunology*
Chemical
Reg. No./Substance:
0/Influenza Vaccines; 0/Vaccines, Inactivated

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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