| Maternal immunization with P fimbriae for the prevention of neonatal pyelonephritis. | |
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MedLine Citation:
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PMID: 2891616 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Rhesus monkeys (Macaca mulatta) were immunized with purified P fimbriae from Escherichia coli during the last trimester of pregnancy. Infants born of these mothers were compared with those from nonimmunized rhesus mothers. A delay in the onset of renal disease after bladder infection showed protection from passive immunization. This was associated with a high antibody titer in serum. In addition to delayed onset of renal infection, a decreased number of immunized monkeys developed pyelonephritis. |
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Authors:
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M B Kaack; J A Roberts; G Baskin; G M Patterson |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Infection and immunity Volume: 56 ISSN: 0019-9567 ISO Abbreviation: Infect. Immun. Publication Date: 1988 Jan |
Date Detail:
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Created Date: 1988-02-09 Completed Date: 1988-02-09 Revised Date: 2009-11-18 |
Medline Journal Info:
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Nlm Unique ID: 0246127 Medline TA: Infect Immun Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1-6 Citation Subset: IM |
Affiliation:
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Department of Urology, Delta Regional Primate Research Center, Tulane University, Covington, Louisiana 70433. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn / immunology* Antibodies, Bacterial / biosynthesis Escherichia coli / immunology Female Fimbriae, Bacterial / immunology* Immunity, Maternally-Acquired* Immunoglobulin G / biosynthesis Immunoglobulin M / biosynthesis Macaca mulatta Pregnancy Pyelonephritis / immunology, pathology, prevention & control* |
| Grant Support | |
ID/Acronym/Agency:
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AM 14681/AM/NIADDK NIH HHS; RR 00164/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Antibodies, Bacterial; 0/Immunoglobulin G; 0/Immunoglobulin M |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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