Document Detail

Maternal heart disease. A survey of a decade in a Danish university hospital.
MedLine Citation:
PMID:  2589039     Owner:  NLM     Status:  MEDLINE    
Among 87 pregnancies complicated by heart disease, delivered during the decade 1977-86, 70 (81%) had a congenital heart malformation, 7 (8%) an acquired heart disease and 10 (11%) arrhythmias or conduction disturbances. The incidence was 0.3%. The corresponding data from a report from Rigshospitalet during the 1950s were: 42%, 49%, and 9%, respectively, and an incidence of 0.9%. Ventricular septal defect (VSD) and atrial septal defect (ASD) were the most frequent malformations. The women were classified according to the NYHA before, during and after the pregnancy. All women except 4 re-entered their original functional class. In 51 cases, ECG showed completely normal sinus rhythm, while in 36, various degrees of arrhythmia or conduction disturbance were found as well as left or right ventricular hypertrophy and/or strains. Nine infants had congenital defects, 4 of which were a heart malformation (4.6%). One infant died. Gestational duration, weight and perinatal mortality did not differ significantly from that of the general population. Two women died, one of primary pulmonary hypertension and one with a rupture of the thoracic aorta. Rheumatic heart disease is no longer a significant factor in relation to pregnancy in Denmark, but congenital heart disease is still of great importance, because more survive and reach the age of fertility. Today most women can be brought safely through pregnancy, but obstetric, cardiologic and anesthesiologic expertise is still mandatory for a successful course and outcome of pregnancies complicated by heart disease.
M Bitsch; C Johansen; A Wennevold; M Osler
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  68     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1989  
Date Detail:
Created Date:  1990-01-11     Completed Date:  1990-01-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  119-24     Citation Subset:  IM    
Department of Gynecology and Obstetrics, Rigshospitalet, Copenhagen, Denmark.
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MeSH Terms
Congenital Abnormalities / epidemiology
Denmark / epidemiology
Fetal Death / epidemiology,  etiology
Heart Diseases* / diagnosis,  epidemiology,  therapy
Infant Mortality
Infant, Newborn
Maternal Mortality
Pregnancy Complications, Cardiovascular* / diagnosis,  epidemiology,  therapy
Pregnancy Outcome*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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