Document Detail

Maternal glucose loading and fetal cardiac function in humans.
MedLine Citation:
PMID:  1671364     Owner:  NLM     Status:  MEDLINE    
Fetal cardiac function determined using M-mode echocardiography was studied subsequent to the maternal intravenous injection of 20 g of glucose. There were 11 appropriate for date infants (AFD), 7 noneventful, light for date infants (LFD) and one high risk fetus in severe toxemia of pregnancy (Case 1), at 32-40 weeks' gestation. The fetal heart rate showed no significant changes after glucose injection in each group. The left ventricular fractional shortening and cardiac output showed significant changes, whereas the right ventricular fractional shortening and cardiac output were unchanged in both AFD and LFD. In Case 1, the adverse change was noted in both left and right cardiac functions, as compared with AFD or LFD. The combined total cardiac output in AFD increased significantly at 5 min following glucose injection, whereas that in LFD did not change significantly. On the other hand, the combined total cardiac output in Case 1 decreased markedly at 5 min after glucose injection. These findings show that the glucose loading in the mother alters cardiac function in the fetus.
T Hata; D Senoh; K Makihara; S Aoki; K Hata; M Kitao
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  34     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-03-08     Completed Date:  1991-03-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  115-9     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Shimane Medical University, Izumo, Japan.
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MeSH Terms
Fetal Heart / physiology,  ultrasonography*
Glucose / administration & dosage
Glucose Tolerance Test*
Maternal-Fetal Exchange
Reg. No./Substance:

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