Document Detail

Maternal glucose administration for facilitating tests of fetal wellbeing.
MedLine Citation:
PMID:  22972062     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Antenatal maternal glucose administration has been suggested to improve the efficiency of antepartum fetal heart rate testing.
OBJECTIVES: The objective of this review was to assess the merits or adverse effects of antenatal maternal glucose administration in conjunction with tests of fetal wellbeing.
SEARCH METHODS: We searched the Cochrane Pregnancy and Childbirth Group's Trials Register (6 July 2012).
SELECTION CRITERIA: All published and unpublished randomized controlled trials assessing the merits of antenatal maternal (oral or intravenous) glucose administration in conjunction with tests of fetal wellbeing.
DATA COLLECTION AND ANALYSIS: Both review authors independently extracted data and assessed trial quality. Authors of published and unpublished trials were contacted for further information.
MAIN RESULTS: A total of two trials, involving 708 participants, were included. Antenatal maternal glucose administration did not decrease the incidence of non-reactive antenatal cardiotocography tests.
AUTHORS' CONCLUSIONS: Antenatal maternal glucose administration has not been shown to reduce non-reactive cardiotocography. More trials are needed to further substantiate this and to determine not only the optimum dose, but also to evaluate the efficacy, predictive reliability, safety and perinatal outcome of glucose administration in conjunction with cardiotocography and also other tests of fetal wellbeing.
Kelvin H Tan; Antoinette Sabapathy
Publication Detail:
Type:  Journal Article; Meta-Analysis; Review     Date:  2012-09-12
Journal Detail:
Title:  The Cochrane database of systematic reviews     Volume:  9     ISSN:  1469-493X     ISO Abbreviation:  Cochrane Database Syst Rev     Publication Date:  2012  
Date Detail:
Created Date:  2012-09-13     Completed Date:  2012-10-30     Revised Date:  2013-06-28    
Medline Journal Info:
Nlm Unique ID:  100909747     Medline TA:  Cochrane Database Syst Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  CD003397     Citation Subset:  IM    
Department of Maternal Fetal Medicine, KK Women’s and Children’s Hospital, Singapore, Singapore.
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MeSH Terms
Administration, Oral
Cardiotocography / methods*
Glucose / administration & dosage*
Heart Rate, Fetal / drug effects,  physiology
Injections, Intravenous
Prenatal Diagnosis / methods
Randomized Controlled Trials as Topic
Single-Blind Method
Reg. No./Substance:
Update Of:
Cochrane Database Syst Rev. 2001;(4):CD003397   [PMID:  11687202 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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