Document Detail

Maternal genital Chlamydia trachomatis infection and the risk of preterm labor.
MedLine Citation:
PMID:  7705529     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the association between maternal genital Chlamydia trachomatis infection in pregnancy and the risk of preterm labor. The hypothesis tested was that a greater proportion of women experiencing preterm labor would have Chlamydia trachomatis than controls who were not experiencing preterm labor. METHODS: A case-control study in Yaoundé (Cameroon), involving 126 women of gestational age between 28 and 34 weeks, using serology and cervical swab cultures. Data analysis involved simple comparative descriptive statistics as well as univariate and multivariate analysis. RESULTS: The odds of experiencing preterm labor and having genital chlamydial infection were 72.59 (exact 95% C.I. 0.99-7.14); O.R.MH (Mantel-Haenszel) 2.80 (approximate 95% C.I. 1.13-6.97) using serological tests. The proportion of women with positive cervical swab cultures was statistically significantly different between cases and controls (Fisher's exact test, P = 0.02). CONCLUSION: Routine screening and treatment of pregnant women with Chlamydia trachomatis (along with their partners) may be beneficial in reducing the incidence of preterm labor and delivery and hence the perinatal mortality rate.
P C Ngassa; J A Egbe
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  47     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-05-05     Completed Date:  1995-05-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  241-6     Citation Subset:  IM    
Clinical Epidemiology Unit (CEU), University of Yaoundé I, Cameroon.
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MeSH Terms
Case-Control Studies
Chlamydia Infections / complications,  epidemiology*
Chlamydia trachomatis*
Fetal Death / etiology,  prevention & control
Multivariate Analysis
Obstetric Labor, Premature / etiology,  prevention & control*
Pregnancy Complications, Infectious / epidemiology*
Uterine Cervical Diseases / complications,  epidemiology*

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