Document Detail

Maternal floor infarction of the placenta: association with central nervous system injury and adverse neurodevelopmental outcome.
MedLine Citation:
PMID:  11948388     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To compare cranial ultrasound studies and neurodevelopmental outcome of preterm infants affected by maternal floor infarction (MFI) of the placenta to gestational age-matched controls over an 8-year period from a single institution. STUDY DESIGN: Retrospective case/control study. RESULTS: Compared to gestational age-matched controls, infants born to mothers with MFI had a higher incidence of CNS injury on neonatal cranial ultrasound examinations and at follow-up were more likely to have a suspicious or abnormal neurologic examination. MFI cases had lower developmental scores in all areas tested and were more likely to have neurodevelopmental impairment. CONCLUSION: Infants born to mothers with MFI should have serial neonatal cranial ultrasound examinations to detect CNS injury and neurodevelopmental assessment during early childhood.
Ira Adams-Chapman; Yvonne E Vaucher; Raul F Bejar; Kurt Benirschke; Rebecca N Baergen; Thomas R Moore
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  22     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:    2002 Apr-May
Date Detail:
Created Date:  2002-04-11     Completed Date:  2002-05-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  236-41     Citation Subset:  IM    
Departments of Pediatrics/Division of Neonatology, Pathology and Reproductive Medicine, University of California at San Diego, San Diego, CA, USA.
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MeSH Terms
Case-Control Studies
Central Nervous System / injuries
Central Nervous System Diseases / etiology*
Developmental Disabilities*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / etiology*
Infarction / complications*
Intracranial Hemorrhages / etiology
Placenta / blood supply*
Placental Circulation*
Pregnancy Outcome*
Skull / ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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