Document Detail


Maternal floor infarction associated with oligohydramnios and cystic renal dysplasia: report of 2 cases.
MedLine Citation:
PMID:  20017640     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Maternal floor infarction (MFI) is an unusual, idiopathic placental disorder characterized by deposition of amorphous fibrinoid material along the maternal aspect of the intervillous space. This condition is associated with poor perinatal outcome-in particular, spontaneous abortion-fetal growth restriction, and stillbirth, with a high recurrence rate in subsequent pregnancies. It is unknown whether MFI is a single entity or the common end point of different insults. Most studies have linked MFI to underlying maternal disorders including gestational hypertension, autoimmune disease, and thrombophilia. In contrast, there have been only a few case reports regarding the possibility of a fetal basis for MFI. We report 2 cases of MFI in fetuses who suffered from oligohydramnios as a result of bilateral cystic renal dysplasia. These 2 cases suggest the concept that fetoplacental factors may also play a role in MFI. It is speculated that the mechanism might involve changes in intrauterine hydrostatic pressure gradients.
Authors:
Mana Taweevisit; Paul Scott Thorner
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society     Volume:  13     ISSN:  1093-5266     ISO Abbreviation:  Pediatr. Dev. Pathol.     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-05-04     Completed Date:  2010-06-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9809673     Medline TA:  Pediatr Dev Pathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  116-20     Citation Subset:  IM    
Affiliation:
Department of Pathology, Faculty of Medicine, Chulalongkorn University, 1873 King Rama IV Street, Pathumwan, Bangkok, 10330 Thailand. dr.mana4@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Fetal Diseases / pathology*
Humans
Infarction / complications,  pathology*
Kidney Diseases, Cystic / complications,  pathology*
Male
Oligohydramnios / pathology*
Placenta / blood supply,  pathology
Placenta Diseases / pathology*
Pregnancy
Stillbirth
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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