| Maternal and fetal survival following surgery and chemotherapy of endodermal sinus tumor of the ovary during pregnancy: a case report. | |
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MedLine Citation:
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PMID: 2464778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An ovarian endodermal sinus tumor was found in a patient with a 15-week intrauterine gestation. She received conservative surgery and six courses of combination chemotherapy from 16 weeks' gestation, and delivered a normal term infant at 37 weeks' gestation. Two other courses of combination chemotherapy including cisplatin were added. No residual tumor was found at subsequent exploration, and she is alive 33 months after the original diagnosis without any evidence of recurrence. We believe this is the first reported case of maternal survival past 2 years and the earliest chemotherapy done in the early second trimester of pregnancy without resulting in fetal abnormalities. |
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Authors:
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D S Kim; M I Park |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 73 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1989 Mar |
Date Detail:
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Created Date: 1989-03-23 Completed Date: 1989-03-23 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 503-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, School of Medicine, Hanyang University, Seoul, Korea. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antineoplastic Combined Chemotherapy Protocols / therapeutic use* Bleomycin / administration & dosage Cisplatin / administration & dosage Combined Modality Therapy Cyclophosphamide / administration & dosage Dactinomycin / administration & dosage Fallopian Tubes / surgery Female Humans Infant, Newborn Male Mesonephroma / mortality, therapy* Ovarian Neoplasms / mortality, therapy* Ovariectomy Pregnancy Pregnancy Complications, Neoplastic / mortality, therapy* Vinblastine / administration & dosage Vincristine / administration & dosage |
| Chemical | |
Reg. No./Substance:
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0/PVB protocol; 0/VAC protocol; 11056-06-7/Bleomycin; 15663-27-1/Cisplatin; 50-18-0/Cyclophosphamide; 50-76-0/Dactinomycin; 57-22-7/Vincristine; 865-21-4/Vinblastine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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