Document Detail


Maternal fetal and placental gastrin concentrations.
MedLine Citation:
PMID:  7081644     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The radioimmunoassay technique was used to measure maternal, placental and fetal serum gastrin levels. A progressive increase in gastrin levels occurred with the advance of pregnancy reaching mean peak levels of 62 (SEM 12) pg/ml during labour. Umbilical artery (74 pg/ml: SEM 7) or vein (73 pg/ml: SEM 7) gastrin concentration was higher than maternal gastrin levels. Placental gastrin concentration was 840 pg/g (SEM 96) and amniotic fluid contained 22 pg/ml (SEM 2). This study implies that one of the reasons for increased maternal gastric residue seen during pregnancy is due to an increased serum gastrin concentration. Also the advanced stage of development of gastrointestinal system of the newborn is in accord with high fetal gastrin concentration.
Authors:
R R Attia; A M Ebeid; J E Fischer; N G Goudsouzian
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Anaesthesia     Volume:  37     ISSN:  0003-2409     ISO Abbreviation:  Anaesthesia     Publication Date:  1982 Jan 
Date Detail:
Created Date:  1982-07-19     Completed Date:  1982-07-19     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370524     Medline TA:  Anaesthesia     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  18-21     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniotic Fluid / analysis
Female
Fetal Blood / analysis*
Gastrins / analysis,  blood*
Humans
Placenta*
Pregnancy*
Grant Support
ID/Acronym/Agency:
RR 05486 13/RR/NCRR NIH HHS
Chemical
Reg. No./Substance:
0/Gastrins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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