Document Detail


Maternal and fetal exposure to bisphenol A in Korea.
MedLine Citation:
PMID:  18577445     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Bisphenol A (BPA) is a well-known endocrine disrupter used widely. Despite the potential risk of human exposure to BPA, little information exists concerning maternal and fetal exposure to BPA during pregnancy in Korea. This study purposed to evaluate the correlation between maternal and fetal exposure, and to determine exposure levels to BPA in Korean pregnant women and their fetuses. Maternal blood and umbilical cord blood were collected from 300 subjects, and total BPA levels were measured. Blood BPA concentrations ranged from non-detectable to 66.48 microg/L in pregnant women and from non-detectable to 8.86 microg/L in umbilical cords. Serum BPA levels in most pregnant women were higher than in corresponding fetal umbilical cords and a positive correlation was found between in maternal and fetal BPA concentrations (p<0.05).
Authors:
Young Joo Lee; Heui-Young Ryu; Hyun-Kyung Kim; Chung Sik Min; Jin Hee Lee; Eunhee Kim; Bong Hyun Nam; Joo Hong Park; Jin Young Jung; Dong Deuk Jang; Eun Young Park; Kwan-Hee Lee; Jin-Young Ma; Hey-Sung Won; Moon-Whan Im; Jong-Han Leem; Yun-Chul Hong; Hae-Seong Yoon
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-05-25
Journal Detail:
Title:  Reproductive toxicology (Elmsford, N.Y.)     Volume:  25     ISSN:  0890-6238     ISO Abbreviation:  Reprod. Toxicol.     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-07-22     Completed Date:  2009-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8803591     Medline TA:  Reprod Toxicol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  413-9     Citation Subset:  IM    
Affiliation:
Human Exposure Assessment Team, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, Republic of Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Endocrine Disruptors / blood*
Environmental Monitoring
Estrogens, Non-Steroidal / blood*
Female
Fetal Blood / chemistry
Humans
Korea
Maternal Exposure
Maternal-Fetal Exchange
Phenols / blood*
Pregnancy
Chemical
Reg. No./Substance:
0/Endocrine Disruptors; 0/Estrogens, Non-Steroidal; 0/Phenols; 80-05-7/bisphenol A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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