| Maternal and fetal catecholamines and uterine incision-to-delivery interval during elective cesarean. | |
| | |
MedLine Citation:
|
PMID: 2107478 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The fetal sympathoadrenal system is activated during periods of intrauterine stress such as inadequate uterine perfusion. During cesarean, the period of interruption of utero-placental blood flow is extended as the time interval from uterine incision to delivery increases. An increasing uterine incision-to-delivery interval with spinal or general anesthesia has been associated with a poorer neonatal outcome. This association has not been demonstrated previously in patients undergoing cesarean delivery under epidural anesthesia. We investigated the correlation between prolonged uterine incision-to-delivery intervals, fetal catecholamine concentrations, and fetal blood gas values at delivery in 25 parturients undergoing cesarean under epidural anesthesia and in 28 under spinal anesthesia. Infants delivered after prolonged uterine incision-to-delivery intervals had significantly lower pH values in both the epidural and spinal groups. With longer uterine incision-to-delivery intervals, umbilical arterial norepinephrine concentrations were increased significantly. Umbilical arterial pH values were significantly lower in infants with higher umbilical arterial catecholamine concentrations. The importance of minimizing the uterine incision-to-delivery interval, regardless of the type of anesthetic selected, is demonstrated. |
| | |
Authors:
|
A M Bader; S Datta; G R Arthur; E Benvenuti; M Courtney; M Hauch |
Related Documents
:
|
8160948 - Postoperative apnoea in infants. 19592408 - Perioperative use of dexmedetomidine in an infant with familial dysautonomia. 2309548 - Does ephedrine influence newborn neurobehavioural responses and spectral eeg when used ... 1020638 - Pneumothorax during anesthesia with changes in ecg. 6988018 - Postnatal changes in urinary prostaglandin e excretion in premature infants. 7804048 - Birth weight and later socioeconomic disadvantage: evidence from the 1958 british cohor... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Obstetrics and gynecology Volume: 75 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 1990 Apr |
Date Detail:
|
Created Date: 1990-04-26 Completed Date: 1990-04-26 Revised Date: 2009-10-26 |
Medline Journal Info:
|
Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 600-3 Citation Subset: AIM; IM |
Affiliation:
|
Department of Anesthesia, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anesthesia, Epidural Anesthesia, Obstetrical Anesthesia, Spinal Carbon Dioxide / blood Cesarean Section* Epinephrine / blood* Female Fetal Blood / analysis* Humans Hydrogen-Ion Concentration Norepinephrine / blood* Oxygen / blood Pregnancy Time Factors |
| Chemical | |
Reg. No./Substance:
|
124-38-9/Carbon Dioxide; 51-41-2/Norepinephrine; 51-43-4/Epinephrine; 7782-44-7/Oxygen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dealing with the stress of an HIV-positive diagnosis at an Army medical center.
Next Document: Heparin therapy for pregnant women with lupus anticoagulant or anticardiolipin antibodies.