Document Detail


Maternal and fetal alphafetoprotein (AFP) levels at term. Relation to sex, weight and gestation of the infant.
MedLine Citation:
PMID:  2409735     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Serum alpha-fetoprotein (AFP) was measured in maternal, cord arterial and venous blood. Samples were collected at the time of vaginal delivery from 105 women at 36-42 weeks' gestation. There was a significant correlation between maternal, cord arterial and venous AFP. Umbilical cord arterial and venous AFP levels were considerably higher in male infants than in females. Umbilical AFP levels declined with lengthening gestation and increasing birthweight for both male and female infants and a similar pattern was seen in the mother. Fetal AFP levels were significantly higher in subjects giving birth at 40 weeks whose infants had a birthweight below the population mean vis-à-vis those above the mean. It is concluded that the absolute size of the fetus as well as gestational age may play a significant role in determining maternal and fetal AFP concentration.
Authors:
B C Obiekwe; N Malek; M J Kitau; T Chard
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Acta obstetricia et gynecologica Scandinavica     Volume:  64     ISSN:  0001-6349     ISO Abbreviation:  Acta Obstet Gynecol Scand     Publication Date:  1985  
Date Detail:
Created Date:  1985-08-16     Completed Date:  1985-08-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370343     Medline TA:  Acta Obstet Gynecol Scand     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  251-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Birth Weight
Embryonic and Fetal Development
Female
Fetal Blood / analysis
Gestational Age
Humans
Infant, Newborn
Male
Pregnancy
Sex Factors
alpha-Fetoproteins / analysis*
Chemical
Reg. No./Substance:
0/alpha-Fetoproteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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