| Maternal dietary fat type influences the growth and fatty acid composition of newborn and weanling rats. | |
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MedLine Citation:
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PMID: 1941255 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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To determine whether the long-term consumption of different amounts or types of fat by female rats affects the growth and development of their progeny, Wistar rats were fed from weaning either a low fat diet (4.5% by weight) or one of three high fat (32%) diets containing predominantly beef tallow (high saturated fat), corn oil (high polyunsaturated fat) or equal portions of tallow and corn oil (high mixed fat). Offspring were killed at birth or weaning. Weight of newborn pups was lower with maternal consumption of high polyunsaturated fat diets. Carcass composition of newborn pups and body weight of weanling rats was unaffected by maternal diet. The percentage of carcass lipid was greater in weanling rats from all high fat-fed dams. In both newborn pups and weanling rats, percent composition in carcass lipids of 16:0, 16:1 and 18:1 fatty acids generally decreased and 18:2 increased as the high fat maternal diet became more unsaturated. The consumption of diets high in polyunsaturated fatty acids prior to and throughout gestation thus seemed to have a transitory effect on reducing fetal growth in rats. |
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Authors:
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D B Hausman; H M McCloskey; R J Martin |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of nutrition Volume: 121 ISSN: 0022-3166 ISO Abbreviation: J. Nutr. Publication Date: 1991 Dec |
Date Detail:
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Created Date: 1991-12-26 Completed Date: 1991-12-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0404243 Medline TA: J Nutr Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1917-23 Citation Subset: IM |
Affiliation:
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Department of Foods and Nutrition, University of Georgia, Athens 30602. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn / metabolism* Body Weight Dietary Fats / metabolism*, pharmacology Embryonic and Fetal Development / drug effects* Female Maternal-Fetal Exchange Pregnancy Rats Rats, Inbred Strains Weaning |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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