Document Detail

Maternal deaths due to liver disease in Malaysia.
MedLine Citation:
PMID:  19839149     Owner:  NLM     Status:  MEDLINE    
Liver disease is an important and serious condition in pregnancy. The Confidential Enquiries Into Maternal Deaths in Malaysia showed that there were 23 maternal deaths attributed to liver disease between 1991-1994. Over the same period, there were 1066 reported maternal deaths with 929 of them being due to direct and indirect causes. Thus 2.15% of such deaths were due to liver disease in Malaysia. The three main causes of maternal deaths due to liver disease in pregnancy were hepatitis (6 cases), acute fatty liver in pregnancy (6 cases) and septicaemia (4 cases). Liver disease is common at a mean of thirty weeks of gestation with a preponderance to women of low parity. Only two patients in this series had no antenatal care. The majority of cases (45.8%) presented between 28-37 weeks of gestation. All cases delivered by spontaneous vaginal delivery. Remediable factors that were identified included failure to appreciate the severity of disease. Case summaries of all the cases of maternal deaths due to liver disease are discussed and a guideline to management of liver disease in pregnancy presented.
J Ravindran; R Jayadev; S R Lachmanan; I Merican
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Medical journal of Malaysia     Volume:  55     ISSN:  0300-5283     ISO Abbreviation:  Med. J. Malaysia     Publication Date:  2000 Jun 
Date Detail:
Created Date:  2009-10-20     Completed Date:  2009-12-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361547     Medline TA:  Med J Malaysia     Country:  Malaysia    
Other Details:
Languages:  eng     Pagination:  209-19     Citation Subset:  IM    
Department of O & G, Seremban Hospital, 70300 Seremban.
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MeSH Terms
Cause of Death
Liver Diseases / ethnology,  mortality*,  physiopathology
Malaysia / epidemiology
Maternal Mortality / ethnology,  trends*
Young Adult

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