Document Detail

Maternal chronic infection as a risk factor in preterm low birth weight infants: the link with periodontal infection.
MedLine Citation:
PMID:  15368875     Owner:  NLM     Status:  MEDLINE    
In the past decade, there has been mounting scientific evidence suggesting that periodontal disease may play an important role as a risk factor for adverse pregnancy outcomes. This article focuses on the definition, incidence, risk factors associated with preterm low birthweight infants (PLBW), the evidence linking chronic infections and PLBW, and the scientific evidence linking periodontal infections with adverse pregnancy outcomes. Additionally, this review summarizes the current epidemiological studies on the PLBW/infection relation and makes conclusions based on these results. Data from a limited number of studies available support the hypothesis that periodontal disease may act as a risk factor for PLBW infants. The fetal exposure to different periodontal pathogens needs to be confirmed, the mechanisms associated with the potential passage of periodontal bacteria across the placental barrier, and the efficacy of different periodontal treatments in reducing the risk for PLBW need to be studied further.
Andrés R Sánchez; Leo I Kupp; Phillip J Sheridan; Diego R Sánchez
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the International Academy of Periodontology     Volume:  6     ISSN:  1466-2094     ISO Abbreviation:  J Int Acad Periodontol     Publication Date:  2004 Jul 
Date Detail:
Created Date:  2004-09-16     Completed Date:  2004-10-18     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  100888553     Medline TA:  J Int Acad Periodontol     Country:  England    
Other Details:
Languages:  eng     Pagination:  89-94     Citation Subset:  D    
Division of Periodontics, Department of Dental Specialties, Mayo Clinic W4A, 200 First Street SW, Rochester, MN 55905, USA.
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MeSH Terms
Bacterial Infections / complications
Chronic Disease
Infant, Low Birth Weight*
Infant, Newborn
Obstetric Labor, Premature / etiology*
Periodontitis / complications*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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