| Maternal characteristics and twin gestation outcomes over 10 years: impact of conception methods. | |
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MedLine Citation:
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PMID: 22608318 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To compare maternal characteristics and obstetric outcomes of spontaneously conceived (SC) and after-fertility treatment (FT) twins. DESIGN: Retrospective study. SETTING: Single tertiary center (university hospital). PATIENT(S): All twin pregnancies (n = 1,239) delivered ≥24 weeks of gestation and classified by the mode of conception. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Maternal age, prematurity, preterm rupture of membranes (PROM), delivery mode, cervical insufficiency, preeclampsia/HELLP (hemolysis, elevated liver enzymes, low platelet count) syndrome, gestational diabetes, and postpartum hemorrhage. RESULT(S): Of 1,239 mothers evaluated, 34.4% received FT. We observed a continuous 3.2-year mean increase in maternal age over time in the FT population. The FT group had statistically significantly higher rates of women ≥35 years of age versus the SC group (37.6% vs. 22.9%). Mean maternal age (32.5 vs. 30.1 years) and the rates of cesarean delivery (72.3% vs. 63.9%), dichorionic twin prematurity (67.7% vs. 59.6%), postpartum hemorrhage (9.9% vs. 6%), PROM (2.3% vs. 0.6%), and cervical insufficiency (17.6% vs. 10%) were statistically significantly higher in the FT group. Preeclampsia/HELLP syndrome and gestational diabetes showed no significantly significant difference. CONCLUSION(S): Mothers of twins after FT were statistically significantly older and had higher rates of prematurity, cesarean delivery, and obstetric morbidity. |
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Authors:
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Christian Bamberg; Christina Fotopoulou; Philipp Neissner; Torsten Slowinski; Joachim W Dudenhausen; Hans Proquitte; Christoph Bührer; Wolfgang Henrich |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-5-17 |
Journal Detail:
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Title: Fertility and sterility Volume: - ISSN: 1556-5653 ISO Abbreviation: - Publication Date: 2012 May |
Date Detail:
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Created Date: 2012-5-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Obstetrics, Charité University Medical Center, Berlin, Germany. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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