Document Detail


Maternal characteristics and cervical length in the prediction of spontaneous early preterm delivery in twins.
MedLine Citation:
PMID:  16647922     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The purpose of this study was to examine the value of combining maternal characteristics and measurement of cervical length at 22 to 24 weeks in the prediction of spontaneous early preterm delivery. STUDY DESIGN: Cervical length was measured by transvaginal sonography at 22 to 24 weeks in 1163 twin pregnancies attending for routine antenatal care. Logistic regression analysis was used to examine the effect of maternal demographic characteristics and cervical length on the risk of spontaneous early preterm delivery. RESULTS: The rate of spontaneous delivery before 32 weeks was 6.5%. The rate of early delivery was inversely related to cervical length, and for a false-positive rate of 10%, the detection rate of early delivery was 65.3%. The respective detection rate for maternal characteristics and obstetric history was 26.4%. Logistic regression analysis demonstrated that the only significant independent predictor of spontaneous early delivery was cervical length. CONCLUSION: In twins, the prediction of spontaneous early preterm delivery by measurement of cervical length at 22 to 24 weeks is not improved by maternal characteristics.
Authors:
Meekai S To; Eduardo B Fonseca; Francisca S Molina; Ana M Cacho; Kypros H Nicolaides
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-04-21
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  194     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-05-01     Completed Date:  2006-06-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1360-5     Citation Subset:  AIM; IM    
Affiliation:
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London, United Kingdom.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Cervix Uteri / ultrasonography*
Female
Humans
Incidence
Logistic Models
Medical Records
Middle Aged
Obstetric Labor, Premature / epidemiology,  etiology*
Predictive Value of Tests
Pregnancy
Pregnancy, Multiple*
ROC Curve
Risk Factors
Twins*

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