Document Detail


Maternal breast milk odour induces frontal lobe activation in neonates: a NIRS study.
MedLine Citation:
PMID:  20675084     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We used near-infrared spectroscopy (NIRS) to examine differences in neonates' orbito-frontal cortical activation in response to the odours of maternal breast milk and formula milk in terms of changes in the oxygenation of cerebral blood flow. Twenty-six healthy neonates were tested in their cribs while they slept in a silent room. The neonates were exposed to each olfactory stimulus by an experimenter. NIRS monitoring was performed using optodes placed above the bilateral anterior orbito-frontal gyri. The differences in oxygenated haemoglobin (oxy-Hb) values between baseline and stimulation were defined as the change in oxy-Hb. The degrees of change were calculated by an analysis of variance (ANOVA). A 2 (stimulus: breast milk and formula milk) × 2 (probe location: right and left) ANOVA showed that the odour of maternal breast milk (right/left: M=0.28/0.48) induced a significantly (F=6.36, p<0.05) greater increase in the oxygenated blood of the orbito-frontal region than did the odour of formula milk (right/left: M=-0.03/-0.07). Differences in the intensity of odour had no significant influence on the blood oxygenation of the orbito-frontal region. Maternal breast milk odour increased oxygenated blood flow in the orbito-frontal region to a greater extent than did formula milk odour. These results suggest that neonates can distinguish between the odours of maternal breast milk versus formula.
Authors:
Shiori Aoyama; Tamotsu Toshima; Yuri Saito; Nakao Konishi; Kyoko Motoshige; Nobutsune Ishikawa; Kazuhiro Nakamura; Masao Kobayashi
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-08-01
Journal Detail:
Title:  Early human development     Volume:  86     ISSN:  1872-6232     ISO Abbreviation:  Early Hum. Dev.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-09     Completed Date:  2011-01-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708381     Medline TA:  Early Hum Dev     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  541-5     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Department of Pediatrics, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan. shiori@setoyama.org
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MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Female
Frontal Lobe / blood supply,  physiology*
Humans
Infant, Newborn
Male
Milk, Human / chemistry*
Odors*
Oxyhemoglobins / analysis
Spectroscopy, Near-Infrared
Chemical
Reg. No./Substance:
0/Oxyhemoglobins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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