| Maternal Smoking During Pregnancy and Childhood Growth Trajectory: A Random Effects Regression Analysis. | |
| | |
MedLine Citation:
|
PMID: 22277789 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Background: Although maternal smoking during pregnancy has been reported to have an effect on childhood overweight/obesity, the impact of maternal smoking on the trajectory of the body mass of their offspring is not very clear. Previously, we investigated this effect by using a fixed-effect model. However, this analysis was limited because it rounded and categorized the age of the children. Therefore, we used a random-effects hierarchical linear regression model in the present study.Methods: The study population comprised children born between 1 April 1991 and 31 March 1999 in Koshu City, Japan and their mothers. Maternal smoking during early pregnancy was the exposure studied. The body mass index (BMI) z-score trajectory of children born to smoking and non-smoking mothers, by gender, was used as the outcome. We modeled BMI trajectory using a 2-level random intercept and slope regression.Results: The participating mothers delivered 1619 babies during the study period. For male children, there was very strong evidence that the effect of age in months on the increase in BMI z-score was enhanced by maternal smoking during pregnancy (P < 0.0001). In contrast, for female children, there was only weak evidence for an interaction between age in months and maternal smoking during pregnancy (P = 0.054), which suggests that the effect of maternal smoking during pregnancy on the early-life BMI trajectory of offspring differed by gender.Conclusions: These results may be valuable for exploring the mechanism of fetal programming and might therefore be clinically important. |
| | |
Authors:
|
Kohta Suzuki; Naoki Kondo; Miri Sato; Taichiro Tanaka; Daisuke Ando; Zentaro Yamagata |
Related Documents
:
|
18502009 - Mandibular gingival arteriovenous malformation in pregnancy. 11731889 - Perinatal management of fetal cardiac anomalies in a specialized obstetric-pediatrics c... 21116739 - Hemodynamic and neurohumoral profile in patients with different types of hypertension i... 9435619 - Dose-dependent reduction of cardiac transmembrane potential by high-intensity electrica... 9065149 - Central hemodynamic changes associated with pregnancy in a long-term cardiac transplant... 19574179 - Cardiac tamponade: an alternative procedure for late feticide. 1536379 - Effect of chloroquine chemoprophylaxis during pregnancy on birth weight: results of a r... 21372369 - A study on teenage pregnant mothers attending primary health centers of kempegowda inst... 11870139 - The "vanishing embryo" phenomenon in an oocyte donation programme. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-1-21 |
Journal Detail:
|
Title: Journal of epidemiology / Japan Epidemiological Association Volume: - ISSN: 1349-9092 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
|
Created Date: 2012-1-26 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9607688 Medline TA: J Epidemiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Center for Birth Cohort Studies, Interdisciplinary Graduate School of Medicine and Engineering, University of Yamanashi. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Syringotropic Melanoma: A Variant of Melanoma With Prominent Involvement of Eccrine Apparatus and Ri...
Next Document: Effects of Maternal 5,10-Methylenetetrahydrofolate Reductase C677T and A1298C Polymorphisms and Toba...