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Maternal Preeclampsia Protects Preterm Infants against Severe Retinopathy of Prematurity.
MedLine Citation:
PMID:  20888573     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To study the influence of maternal preeclampsia on the occurrence of retinopathy of prematurity.
STUDY DESIGN: A prospective cohort study of 324 preterm neonates with birth weight ≤1500 g and gestational age ≤32 weeks. Multiple maternal and perinatal factors were analyzed for association and confounding by multiple logistic regression analysis.
RESULTS: Mean birth weight was 1128 ± 240 g, and mean gestational age 29.7 ± 1.9 weeks. Twenty-four newborns (7.4%) had severe retinopathy of prematurity; 97 had any stage of retinopathy, and 227 had no retinopathy of prematurity. Preeclampsia and complete antenatal steroid treatment course reduced the risk for any stage of retinopathy of prematurity by 60% and 54%, respectively. Preeclampsia reduced the risk for severe retinopathy of prematurity by 80%.
CONCLUSIONS: Preeclampsia lowered the risk for occurrence of any stage and severe retinopathy of prematurity in very low birth weight infants.
Authors:
João Borges Fortes Filho; Marlene C Costa; Gabriela U Eckert; Paula G B Santos; Rita C Silveira; Renato S Procianoy
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Publication Detail:
Type:  Journal Article     Date:  2010-10-08
Journal Detail:
Title:  The Journal of pediatrics     Volume:  158     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  372-6     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2011 Mosby, Inc. All rights reserved.
Affiliation:
Departments of Pediatrics and Ophthalmology, Newborn Section, Universidade Federal do Rio Grande do Sul and Hospital de Clinicas de Porto Alegre, Porto Alegre, RS, Brazil.
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