Document Detail

Maternal Pre-pregnancy Body Mass Index and Offspring Temperament and Behavior at 1 and 2 Years of Age.
MedLine Citation:
PMID:  22983494     Owner:  NLM     Status:  Publisher    
Recent research suggests that fetal exposure to increased maternal body mass index (BMI) during pregnancy may be associated with psychopathology later in life. When this link first emerges, and if it is due to intrauterine exposures or confounding variables is not known. We therefore assessed associations between maternal pre-pregnancy BMI and: (1) temperament at 1 year of age, and (2) Child Behavior Checklist internalizing and externalizing scales at age 2 in the 2900 mothers and infants enrolled in the Western Australian Pregnancy Study. Pre-pregnancy BMI was positively associated with externalizing scores (β = 0.131, 95 % CI 0.013-0.249) at age 2, even after adjustment for confounders, but not with internalizing scores or an increased risk of difficult temperament. These data suggest that fetal exposure to increased maternal BMI is associated with elevated levels of behavior problems as early as age 2, and that this may be linked to the intrauterine environment.
Ryan J Van Lieshout; Louis A Schmidt; Monique Robinson; Alison Niccols; Michael H Boyle
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-15
Journal Detail:
Title:  Child psychiatry and human development     Volume:  -     ISSN:  1573-3327     ISO Abbreviation:  Child Psychiatry Hum Dev     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  1275332     Medline TA:  Child Psychiatry Hum Dev     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Chedoke Division, Department of Psychiatry and Behavioral Neurosciences, McMaster University, Box 2000, Central Building Rm 304, 1200 Main Street West, Hamilton, ON, L8N 3Z5, Canada,
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