Document Detail


Maternal Infection in Pregnancy and Risk of Asthma in Offspring.
MedLine Citation:
PMID:  23338127     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
This study estimates the effect of maternal infections during pregnancy on childhood asthma. One-thousand four-hundred and twenty-eight pregnant women were prospectively followed using structured interviews and chart review until their child's 6th year of life. Infections were identified from outpatient and hospital visits. Childhood asthma was defined as physician diagnosis with symptoms at age six. Adjusted odds ratios were calculated from multivariable logistic regression models. Six-hundred and thirty-five women experienced an infection during pregnancy. Among antepartum infections, maternal urinary tract infections were significantly associated with childhood asthma (aOR 1.60, 95 % CI 1.12-2.29). Chorioamnionitis and maternal group beta streptococcus colonization were not significantly associated with an increased risk in childhood asthma. This study found an increased risk of asthma in children of women diagnosed with urinary tract infections during pregnancy, while other maternal infections did not increase the risk.
Authors:
Charlene H Collier; Kari Risnes; Errol R Norwitz; Michael B Bracken; Jessica L Illuzzi
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-22
Journal Detail:
Title:  Maternal and child health journal     Volume:  -     ISSN:  1573-6628     ISO Abbreviation:  Matern Child Health J     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9715672     Medline TA:  Matern Child Health J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Robert Wood Johnson Foundation Clinical Scholars Program, Yale University School of Medicine, 333 Cedar St IE-61 SHM, P.O. Box 208088, New Haven, CT, 06520, USA, Charlene.Collier@yale.edu.
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