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Maternal Distress during Pregnancy and Offspring Childhood Overweight.
MedLine Citation:
PMID:  22685634     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Background. Maternal distress during pregnancy increases the intrauterine level of glucocorticoids, which may have long-term health consequences for the child. Objective. To examine if distress as a combined measure of anxiety, depression, and stress of the mother during pregnancy was associated with offspring childhood overweight at age 7. Methods. We performed a cohort study using prospective data from 37,764 women and child dyads from the Danish National Birth Cohort (1996-2002). At a telephone interview at approximately 30 weeks gestation, the women reported whether they felt anxious, depressed, or stressed. The 95 percentile for body mass index in an international reference defined childhood overweight at any given age. Logistic regression was used for the analyses. Results. The prevalence of overweight children at 7 years of age was 9.9%. Prenatal exposure to maternal distress during pregnancy was not associated with childhood overweight at 7 years of age (adjusted OR 1.06 (95% CI 0.96; 1.18)). In analyses stratified on sex, a small tendency of overweight was seen in boys (OR 1.15 (0.99; 1.33)), but not in girls (OR 0.98 (0.85; 1.13)). Conclusions. Maternal distress during pregnancy appeared to have limited, if any, influence on the risk of overweight in offspring at 7 years of age.
Katja Glejsted Ingstrup; Camilla Schou Andersen; Teresa Adeltoft Ajslev; Pernille Pedersen; Thorkild I A Sørensen; Ellen A Nohr
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Publication Detail:
Type:  Journal Article     Date:  2012-05-22
Journal Detail:
Title:  Journal of obesity     Volume:  2012     ISSN:  2090-0716     ISO Abbreviation:  J Obes     Publication Date:  2012  
Date Detail:
Created Date:  2012-06-11     Completed Date:  2012-08-23     Revised Date:  2013-03-04    
Medline Journal Info:
Nlm Unique ID:  101526295     Medline TA:  J Obes     Country:  United States    
Other Details:
Languages:  eng     Pagination:  462845     Citation Subset:  -    
Section for Epidemiology, Department of Public Health, Aarhus University, Bartholins Allé 2, 8000 Aarhus C, Denmark.
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