| Is Maternal Diabetes A Risk Factor For Childhood Obesity? | |
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MedLine Citation:
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PMID: 21955140 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Abstract Objective: Our objective is to determine if there is a relationship between diabetes during pregnancy and childhood obesity, in our inner-city, African-American population. Methods: Pertinent child, neonatal, and maternal pregnancy and delivery data were collected from mothers of children age 2-5 years old. Outcome variable definition was based on children's body mass index (BMI) subgroups; independent variable definition on birthweight subgroups based on customized growth percentiles. Covariates included pre- and postnatal factors. Those covariates marginally related to diabetes (p<0.2) by bivariate analyses, were allowed to compete in logistic regression, with p<0.05 significant. Results: 493 patients were enrolled, of which 35 (7.1%) had diabetes during pregnancy. Children of diabetic mothers were more likely to be obese at age 2-5 years than those of non-diabetics (p=.004). Five of 20 covariates had p<0.2 in bivariate setting. Following stepwise logistic regression, diabetes and maternal prepregnancy BMI were significant determinants of childhood obesity. When large-for-gestational age (LGA) was added into the model, diabetes was no longer significant (p=.105); only LGA (p=0.008) and maternal prepregnancy BMI (p=.032) were significantly associated with childhood obesity. Conclusions: In our inner-city, primarily African-American population, diabetes in pregnancy is significantly related to childhood obesity at age 2-5 years. Well-controlled diabetes during pregnancy that avoids macrosomia may lead to prevention of future childhood obesity as well. |
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Authors:
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Shobha H Mehta; Michael Kruger; Robert J Sokol |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-9-29 |
Journal Detail:
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Title: The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians Volume: - ISSN: 1476-4954 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-9-29 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101136916 Medline TA: J Matern Fetal Neonatal Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Obstetrics, Gynecology, and Women's Health, Henry Ford Health System, Detroit, Michigan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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