| Maternal cytokine balance on the third postpartum day is not affected by the mode of delivery after healthy pregnancies. | |
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MedLine Citation:
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PMID: 20233531 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Previous reports have suggested that delivery is associated with the induction of inflammatory cytokines. The present study was designed to investigate whether increased cytokine production was present on postpartum day 3 after a normal pregnancy and whether any changes were associated with the mode of delivery. In total, 33 pregnant women were enrolled; 18 delivered vaginally and 15 underwent an elective caesarean section (C-section). The levels of 17 cytokines and growth hormones were measured at the beginning of delivery or before anaesthesia and on postpartum day 3. While interleukin (IL)-6 and IL-8 levels decreased significantly postpartum, other cytokine concentrations were comparable before and after delivery. Only IL-7 levels were significantly increased in the C-section patients compared with the vaginal birth patients postpartum. In conclusion, there was no risk of a prolonged maternal inflammatory reaction after an uncomplicated vaginal birth or elective C-section, so it is probably not necessary to consider this as an issue when making a decision on the mode of delivery following uncomplicated pregnancy. |
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Authors:
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B Gyarmati; G Beko; B Szalay; A Cseh; B V?s?rhelyi; A Treszl |
Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of international medical research Volume: 38 ISSN: 0300-0605 ISO Abbreviation: J. Int. Med. Res. Publication Date: 2010 Jan-Feb |
Date Detail:
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Created Date: 2010-03-17 Completed Date: 2010-06-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0346411 Medline TA: J Int Med Res Country: England |
Other Details:
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Languages: eng Pagination: 208-13 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynaecology, Uzsoki Hospital, Budapest, Hungary. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cesarean Section* Cytokines / blood* Delivery, Obstetric* Female Growth Hormone / blood* Humans Pilot Projects Postpartum Period / blood* Pregnancy / blood* |
| Chemical | |
Reg. No./Substance:
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0/Cytokines; 9002-72-6/Growth Hormone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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