Document Detail

Maternal anemia in pregnancy: assessing the effect of routine preventive measures in a malaria-endemic area.
MedLine Citation:
PMID:  23296448     Owner:  NLM     Status:  MEDLINE    
We investigated the effectiveness of routine preventive measures for anemia in Beninese pregnant women during pregnancy. Anemia (hemoglobin < 110 g/L) was common: 68.3% at first antenatal visit (ANV1), 64.7% at second antenatal visit (ANV2), and 40.6% at delivery. Parasitic infections and nutritional deficiencies were the most preventable causes. After intermittent preventive treatment (IPTp) and antihelminthic treatments, malaria prevalence decreased from 15.1% (ANV1) to 4.0% (ANV2) and increased again to 9.6% at delivery. Helminth infections dropped from 11.1% (ANV1) to 7.2% (ANV2) and 2.4% at delivery. Malaria was associated with lower mean hemoglobin on ANV1 and delivery, and iron deficiency was associated with lower mean hemoglobin on ANV1 and ANV2. IPTp and antihelminthic treatments were efficacious to clear parasitic infections and improve hematologic status, whereas the effectiveness of daily iron and folic acid supplements to correct iron and folate deficiencies and decrease anemia was less marked, possibly because of lack of compliance.
Smaïla Ouédraogo; Ghislain K Koura; Florence Bodeau-Livinec; Manfred M K Accrombessi; Achille Massougbodji; Michel Cot
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2013-01-07
Journal Detail:
Title:  The American journal of tropical medicine and hygiene     Volume:  88     ISSN:  1476-1645     ISO Abbreviation:  Am. J. Trop. Med. Hyg.     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-02-07     Completed Date:  2013-04-01     Revised Date:  2014-02-13    
Medline Journal Info:
Nlm Unique ID:  0370507     Medline TA:  Am J Trop Med Hyg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  292-300     Citation Subset:  AIM; IM    
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MeSH Terms
Anemia, Iron-Deficiency / complications,  epidemiology,  prevention & control*
Antimalarials / therapeutic use
Dietary Supplements*
Folic Acid / administration & dosage*
Folic Acid Deficiency / prevention & control
Hemoglobins / analysis
Iron / administration & dosage*
Logistic Models
Malaria / complications,  epidemiology*
Malnutrition / complications,  prevention & control
Multivariate Analysis
Pregnancy Complications, Hematologic / epidemiology,  prevention & control*
Randomized Controlled Trials as Topic
Young Adult
Reg. No./Substance:
0/Antimalarials; 0/Hemoglobins; 935E97BOY8/Folic Acid; E1UOL152H7/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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