Document Detail

Mastalgia: a 3 year Australian study.
MedLine Citation:
PMID:  8179529     Owner:  NLM     Status:  MEDLINE    
Mastalgia is a common but often poorly understood condition with little Australian data available on the subject. Details are presented of 170 patients who have attended a specific mastalgia clinic at the Princess Alexandra Hospital, Brisbane, Queensland, over a 3 year period. The aims and management protocol of the clinic are outlined. The mastalgia sufferer in this study had an average age of 42 years and 87% were multiparous. Cyclical pain occurred in 59% as determined by a daily pain record chart. Unilateral pain occurred in 38%. Lack of previous breast feeding and low levels of regular physical exercise were identified as two significant factors in the history of those attending the clinic. The responses to treatments are outlined. Response rates of 18 and 26% to two commonly used 'natural products', Vitamin B6 and Evening Primrose Oil, respectively, are considered little better than placebo effect. A complete response was achieved in 67% of women who took low dose danazol with minimal side effects. The overall response rate to all treatments was 65% with a mean follow up of 15.5 months for those women who continued to attend the clinic. For women with mastalgia, a systematic approach can achieve relief of pain.
N R Wetzig
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Australian and New Zealand journal of surgery     Volume:  64     ISSN:  0004-8682     ISO Abbreviation:  Aust N Z J Surg     Publication Date:  1994 May 
Date Detail:
Created Date:  1994-06-09     Completed Date:  1994-06-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0373115     Medline TA:  Aust N Z J Surg     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  329-31     Citation Subset:  IM    
University of Queensland Department of Surgery, Princess Alexandra Hospital, Brisbane, Australia.
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MeSH Terms
Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
Breast Diseases / therapy*
Danazol / therapeutic use
Fatty Acids, Essential / therapeutic use
Linoleic Acids
Pain / classification,  physiopathology,  therapy
Pain Measurement
Plant Oils
Progesterone / therapeutic use
Pyridoxine / therapeutic use
Tamoxifen / therapeutic use
Treatment Outcome
gamma-Linolenic Acid
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Fatty Acids, Essential; 0/Linoleic Acids; 0/Plant Oils; 10540-29-1/Tamoxifen; 17230-88-5/Danazol; 506-26-3/gamma-Linolenic Acid; 57-83-0/Progesterone; 65-23-6/Pyridoxine; 65546-85-2/Efamol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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