Document Detail

Mast cells on the surface of the mucous membrane--a general feature of inflammatory reactions in the nose?
MedLine Citation:
PMID:  4059803     Owner:  NLM     Status:  MEDLINE    
A redistribution of mast cells towards the epithelial lining of the nasal mucous membrane has been shown to be a part of the allergic inflammatory reaction in hay fever. This results in an increased number of metachromatically stained cells on the surface of the mucous membrane. The involvement of mast cells in other inflammatory reactions in the human nose is not clarified and this may partly be due to methodological difficulties. Utilizing a recently developed imprint technique, specimens were taken from patients with infectious rhinosinusitis in acute and chronic stages. The total number of mast cells on 2 cm2 of the imprint area were counted. Mast cells in extremely low numbers were found in 5 out of 26 patients. Our results indicate that mast cell migration is not present in patients with infectious inflammatory reactions of the nasal mucous membrane.
I Melén; S Pipkorn; U Pipkorn
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Rhinology     Volume:  23     ISSN:  0300-0729     ISO Abbreviation:  Rhinology     Publication Date:  1985 Sep 
Date Detail:
Created Date:  1985-12-02     Completed Date:  1985-12-02     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0347242     Medline TA:  Rhinology     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  187-90     Citation Subset:  IM    
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MeSH Terms
Epithelium / pathology
Mast Cells / pathology*
Middle Aged
Nasal Mucosa / pathology*
Rhinitis / pathology*
Sinusitis / pathology

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