Document Detail

Massive weight loss following jejunoileal bypass. I. Effects on pulmonary function.
MedLine Citation:
PMID:  847646     Owner:  NLM     Status:  MEDLINE    
Twelve morbidly obese patients had jejunoileal bypass surgery and serial detailed pulmonary function studies done over a one year period. Before operation they showed evidence of a decreased ventilation: perfusion ratio producing a "shuntlike effect" (Pao2 = 73, Paco2 = 37, pH = 7.44) while breathing room air (FIo2 = 0.209). They also had measurements consistent with pure restrictive lung disease. There was a highly significant improvement in the arterial oxygenation over the entire one year period and a significant loss of chest wall mass over the first 6 month period. The improved oxygenation most likely was due to a return of lung volumes toward normal and an improvement in the efficiency of the respiratory muscles.
P Chodoff; A L Imbembo; C L Knowles; P M Margand
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Surgery     Volume:  81     ISSN:  0039-6060     ISO Abbreviation:  Surgery     Publication Date:  1977 Apr 
Date Detail:
Created Date:  1977-05-12     Completed Date:  1977-05-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417347     Medline TA:  Surgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  399-403     Citation Subset:  AIM; IM    
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MeSH Terms
Body Weight*
Ileum / surgery*
Jejunum / surgery*
Obesity / therapy*
Oxygen / blood
Respiratory Function Tests
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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