Document Detail

Massive subchorionic hematoma associated with enoxaparin.
MedLine Citation:
PMID:  17018503     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The use of low-molecular-weight heparins is increasing for the prevention of thromboembolism in pregnancy. Subchorionic hematoma as a complication of anticoagulation therapy is rarely reported. CASE: A persistent, massive subchorionic hematoma was diagnosed in a pregnant patient with atrial fibrillation and mitral stenosis. Enoxaparin was administered to maintain her trough anti-Xa level 0.5 units/mL or higher. The patient's peak anti-Xa levels never exceeded 1.05 units/mL. The patient underwent cesarean delivery at 34 6/7 weeks of gestation for preterm premature rupture of membranes. CONCLUSION: Subchorionic hematoma is a potentially serious complication that can occur in pregnant patients receiving enoxaparin for the prevention of thromboembolism.
Richard H Lee; T Murphy Goodwin
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  108     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-10-04     Completed Date:  2006-10-24     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  787-9     Citation Subset:  AIM; IM    
Los Angeles County-University of Southern California Medical Center, Women's and Children's Hospital, Los Angeles, CA 90033, USA.
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MeSH Terms
Anticoagulants / adverse effects*
Atrial Fibrillation
Cesarean Section
Enoxaparin / adverse effects*
Factor Xa / antagonists & inhibitors
Fetal Membranes, Premature Rupture
Gestational Age
Heart Valve Prosthesis
Hematoma / chemically induced*,  diagnosis*,  ultrasonography
Mitral Valve
Mitral Valve Stenosis
Pregnancy Complications / chemically induced*
Pregnancy Outcome
Thromboembolism / prevention & control
Reg. No./Substance:
0/Anticoagulants; 0/Enoxaparin; EC Xa

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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