Document Detail

Massive sertraline overdose.
MedLine Citation:
PMID:  11054208     Owner:  NLM     Status:  MEDLINE    
Selective serotonin reuptake inhibitor medications are considered relatively safe even in overdose. We report a massive overdose of sertraline with the highest serum sertraline concentration reported to date. Clinical features of this patient were confusion, agitation, myoclonus, hyperreflexia, fever, and creatine kinase elevation. This case may represent serotonin syndrome caused by sertraline overdose alone.
D H Brendel; J A Bodkin; J M Yang
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of emergency medicine     Volume:  36     ISSN:  0196-0644     ISO Abbreviation:  Ann Emerg Med     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2000-12-27     Completed Date:  2000-12-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8002646     Medline TA:  Ann Emerg Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  524-6     Citation Subset:  AIM; IM    
Departments of Psychiatry and Laboratory Medicine, Massachusetts General Hospital, Boston, MA 02114-2698, USA.
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MeSH Terms
Middle Aged
Serotonin Uptake Inhibitors / poisoning*
Sertraline / poisoning*
Reg. No./Substance:
0/Serotonin Uptake Inhibitors; 79617-96-2/Sertraline

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