Document Detail


Massive pulmonary hemorrhage in neonatal infection.
MedLine Citation:
PMID:  766937     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Of 35 newborn infants who died from an infection 19 had postmortem evidence of massive pulmonary hemorrhage. All but 1 of the 19 had evidence of antimortem formation of intravascular fibrin clots in lung tissue. Seventeen infants had low platelet counts. Of the 11 infants in whom coagulation studies were done, 8 had evidence of disseminated intravascular coagulation (DIC) during life. Vasculitis in the lungs, associated with fibrin clots and hemorrhages, was detected in two infants. It is postulated that sepsis is an important cause of hemorrhage in the newborn, probably as a result of the development of DIC.
Authors:
C Y Yeung
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Canadian Medical Association journal     Volume:  114     ISSN:  0008-4409     ISO Abbreviation:  Can Med Assoc J     Publication Date:  1976 Jan 
Date Detail:
Created Date:  1976-05-10     Completed Date:  1976-05-10     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0414110     Medline TA:  Can Med Assoc J     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  135-8     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Bacterial Infections / pathology*
Disseminated Intravascular Coagulation / pathology
Escherichia coli Infections / pathology
Fibrin
Hemoptysis / pathology*
Humans
Infant, Newborn
Infant, Newborn, Diseases / pathology*
Infant, Premature, Diseases / pathology
Klebsiella Infections / pathology
Lung / pathology*
Male
Chemical
Reg. No./Substance:
9001-31-4/Fibrin
Comments/Corrections

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