Document Detail

Massive pulmonary haemorrhage complicating the treatment of acute coronary syndrome.
MedLine Citation:
PMID:  14966076     Owner:  NLM     Status:  MEDLINE    
Antiplatelet medications such as clopidogrel and tirofiban (glycoprotien IIb/IIIa inhibitors) are associated with a reduction in mortality and morbidity and are therefore recommended in the treatment of acute coronary syndromes. Massive pulmonary haemorrhage is a rare complication of both clopidogrel and tirofiban. Pulmonary haemorrhage may easily be mistaken for acute pulmonary oedema, a condition commonly seen in patients with acute coronary syndrome. Physicians need to be aware of this diagnostic dilemma because early treatment increases the chances of patient survival.
D S Gill; K Ng; K-S Ng
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  90     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-02-17     Completed Date:  2004-03-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  England    
Other Details:
Languages:  eng     Pagination:  e15     Citation Subset:  AIM; IM    
Department of Cardiology, The Heart Institute, Tan Tock Seng Hospital, Singapore.
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MeSH Terms
Angina, Unstable / drug therapy*
Diagnostic Errors*
Fatal Outcome
Hemorrhage / chemically induced*,  radiography
Lung Diseases / chemically induced*,  radiography
Middle Aged
Myocardial Infarction / drug therapy*
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
Pulmonary Edema / radiography
Tyrosine / adverse effects*,  analogs & derivatives*
Reg. No./Substance:
0/Platelet Glycoprotein GPIIb-IIIa Complex; 144494-65-5/tirofiban; 55520-40-6/Tyrosine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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