| Massive perivillous fibrinoid causing recurrent placental failure. | |
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MedLine Citation:
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PMID: 12628270 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To establish the incidence, recurrence rate and consequences of massive perivillous fibrinoid. DESIGN: Retrospective analysis of the histology of all placentas with a diagnosis of massive perivillous fibrinoid between 1991 and 1998, together with the maternal case records. SETTING: The histopathology department of the Rotunda Hospital, Dublin, Ireland. POPULATION: A relatively homogeneous group of pregnant women in the northern part of Dublin City, which is the catchment area for the Rotunda Hospital, delivered between 1991 and 1998. METHODS: Retrospective review of archival placental pathology and maternal charts. MAIN OUTCOME MEASURES: The incidence of massive perivillous fibrinoid, perinatal outcome and recurrence rate. RESULTS: The incidence of massive perivillous fibrinoid was 0.028%, with a recurrence rate of approximately 18%. All the infants suffered intrauterine growth restriction; there was a 31% fetal loss rate and a 33% preterm delivery rate. CONCLUSIONS: Massive perivillous fibrinoid is associated with intrauterine death, intrauterine growth restriction and preterm delivery. It has a significant recurrence rate and both the clinical findings of intrauterine growth restriction and the postmortem findings imply a syndrome of chronic placental insufficiency. |
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Authors:
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A L Bane; J E Gillan |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: BJOG : an international journal of obstetrics and gynaecology Volume: 110 ISSN: 1470-0328 ISO Abbreviation: BJOG Publication Date: 2003 Mar |
Date Detail:
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Created Date: 2003-03-11 Completed Date: 2003-04-28 Revised Date: 2005-11-17 |
Medline Journal Info:
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Nlm Unique ID: 100935741 Medline TA: BJOG Country: England |
Other Details:
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Languages: eng Pagination: 292-5 Citation Subset: AIM; IM |
Affiliation:
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Department of Histopathology, Rotunda Hospital, Dublin, Ireland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Habitual
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etiology,
pathology Adult Chorionic Villi / pathology* Female Fetal Death / etiology, pathology Fetal Growth Retardation / etiology, pathology Fibrin / metabolism* Gestational Age Humans Microscopy, Electron Obstetric Labor, Premature / etiology, pathology Placental Insufficiency / etiology*, pathology Pregnancy Recurrence Retrospective Studies |
| Chemical | |
Reg. No./Substance:
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9001-31-4/Fibrin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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