Document Detail

Massive localized lymphedema: A soft tissue process that may present to dermatologists.
MedLine Citation:
PMID:  20514680     Owner:  NLM     Status:  MEDLINE    
Massive localized lymphedema (MLL) is a clinically and histologically distinct entity seen in morbidly obese patients. We describe two obese patients with MLL in the lower abdomen and suprapubic area. Biopsies showed characteristic histologic features of an expanded dermis with lymphangiectases, fibrotic septae and focal fat necrosis. One patient had long-standing hypothyroidism, an association previously reported. This disease is frequently complicated by recurrent cellulitis and may be amenable to surgery. Patients with MLL may present to dermatologists, and this disease has characteristic histopathologic findings that may mimic liposarcoma to the unaware dermatopathologist.
Nadia S Wang; Ruth F Walters; Simon J Warren
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American Journal of dermatopathology     Volume:  32     ISSN:  1533-0311     ISO Abbreviation:  Am J Dermatopathol     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-28     Completed Date:  2010-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7911005     Medline TA:  Am J Dermatopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  380-3     Citation Subset:  IM    
Department of Dermatology, New York University School of Medicine, New York, 10016, USA.
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MeSH Terms
Cellulitis / etiology,  pathology
Lymphedema / etiology*,  pathology*
Middle Aged
Obesity, Morbid / complications*

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