Document Detail


Massive intestinal hemorrhage resulting from a polypoid tumor in the sigmoid colon: an unusual complication of a giant cell tumor of the fifth lumbar vertebra.
MedLine Citation:
PMID:  12642776     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
STUDY DESIGN: Clinicopathologic study of a case of giant cell tumor of the spine. SUMMARY OF BACKGROUND DATA: Giant cell tumors of the spine are uncommon, accounting for 1.3-6.5% of all cases in various series. Because of their location, they may cause neurologic deficits. The treatment consists of excision or curettage and has been claimed to give good results. METHODS: A 33-year-old woman presented with low back pain in 1995; radiologic investigation and biopsy showed features of giant cell tumor involving the fifth lumbar and first sacral vertebrae. Wide excision was performed, but the tumor recurred in 1996 and was curetted. She developed massive intestinal bleeding in 1997 resulting from infiltration of the sigmoid colon by giant cell tumor in the form of a polypoid intraluminal mass. The involved segment of colon was resected, and the patient remained alive, although debilitated, 7 years after initial presentation. RESULTS: Examination of the tumor in the spine and the colon showed typical histology of giant cell tumor with no evidence of malignant transformation. The involved colon was freely mobile and away from the tumor of the spine. CONCLUSION: Giant cell tumor of the spine can result in unusual complication, massive intestinal hemorrhage in our case, which causes considerable morbidity.
Authors:
Louis T C Chow; S M Kumta
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Spine     Volume:  28     ISSN:  1528-1159     ISO Abbreviation:  Spine     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-18     Completed Date:  2003-03-28     Revised Date:  2009-07-09    
Medline Journal Info:
Nlm Unique ID:  7610646     Medline TA:  Spine (Phila Pa 1976)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E121-4     Citation Subset:  IM    
Affiliation:
Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Shatin, Hong Kong. lchow@cuhk.edu.hk
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MeSH Terms
Descriptor/Qualifier:
Adult
Female
Gastrointestinal Hemorrhage / etiology*
Giant Cell Tumors / complications,  diagnosis*,  surgery
Humans
Low Back Pain / etiology
Lumbar Vertebrae / pathology*,  surgery
Neoplasm Recurrence, Local / diagnosis,  surgery
Reoperation
Sigmoid Neoplasms / secondary*,  surgery
Spinal Neoplasms / complications,  diagnosis*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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