| Massive hydroxychloroquine overdose. | |
| | |
MedLine Citation:
|
PMID: 14982575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report a case presenting with massive overdose of hydroxychloroquine who survived without any sequelae. A 17-year-old girl presented to the Emergency Department 45 min after the ingestion of 22 g of hydroxychloroquine in a suicide attempt. We believe this is highest dose yet reported in the medical literature. The patient developed hypotension, life-threatening ventricular arrhythmias and mild hypokalemia. She was managed with saline infusion and dopamine for hypotension, gastric lavage and activated charcoal for decontamination, lidocain, magnesium sulfate and defibrillation for pulseless ventricular tachycardia. Potassium replacement and bicarbonate administration were performed. Quick treatment of hypotension, gastric decontamination, continuous long-term cardiac monitoring, and treatment of arrhythmias are the cornerstones of hydroxychloroquine overdose management. |
| | |
Authors:
|
S Yanturali; E Aksay; O F Demir; R Atilla |
Related Documents
:
|
15163575 - North american snake envenomation: diagnosis, treatment, and management. 15536755 - Medical managers' beliefs about reduced-hour physicians. 15306955 - Periprocedural hypertension: current concepts in management for the vascular surgeon. 18365965 - Delayed chiasmal herniation after transsphenoidal removal of a pituitary adenoma - case... 17078535 - Landfill leachate production, quality and recirculation treatment in northeast china. 12841805 - Potentially inappropriate medication use in community residential care facilities. |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Acta anaesthesiologica Scandinavica Volume: 48 ISSN: 0001-5172 ISO Abbreviation: Acta Anaesthesiol Scand Publication Date: 2004 Mar |
Date Detail:
|
Created Date: 2004-02-25 Completed Date: 2004-06-21 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370270 Medline TA: Acta Anaesthesiol Scand Country: Denmark |
Other Details:
|
Languages: eng Pagination: 379-81 Citation Subset: IM |
Affiliation:
|
Department of Emergency Medicine, Dokuz Eylul University Hospital, Izmir, Turkey. sedat.yanturali@deu.edu.tr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adolescent Antirheumatic Agents / poisoning* Charcoal / therapeutic use Electric Countershock Female Gastric Lavage Humans Hydroxychloroquine / poisoning* Hypokalemia / chemically induced Hypotension / chemically induced Overdose Sorption Detoxification Suicide, Attempted Tachycardia, Ventricular / chemically induced |
| Chemical | |
Reg. No./Substance:
|
0/Antirheumatic Agents; 118-42-3/Hydroxychloroquine; 16291-96-6/Charcoal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Bilateral hypoglossal nerve injury following the use of the laryngeal mask without the use of nitrou...
Next Document: Application of a mandibular nerve block using an indwelling catheter for intractable cancer pain.