Document Detail


Massive hepatosplenomegaly in a child with malaria.
MedLine Citation:
PMID:  12458579     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hypermalarial splenomegaly syndrome (HMS) usually occurs in adults living in malaria-endemic areas. A 7-year-old girl presented with a 7-week history of gradual distention of the abdomen and low grade fever, 8 months after traveling to Ghana, and was subsequently diagnosed with HMS. Presentation at such a young age after very brief exposure to a malaria-endemic area has not been described previously.
Authors:
Shamez Ladhani; Efunbo Dosekun; Vidya Patel; Delane Shingadia
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Pediatric infectious disease journal     Volume:  21     ISSN:  0891-3668     ISO Abbreviation:  Pediatr. Infect. Dis. J.     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-11-29     Completed Date:  2003-01-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8701858     Medline TA:  Pediatr Infect Dis J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1090-2     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Newham General Hospital, London, UK.
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Animals
Antimalarials / therapeutic use
Child
Chloroguanide / therapeutic use
Drug Combinations
Drug Therapy, Combination
Female
Ghana
Hepatomegaly / complications*,  drug therapy,  pathology*
Humans
Liver / pathology
Malaria, Falciparum / complications*,  drug therapy,  pathology*
Pyrimethamine / therapeutic use
Quinine / therapeutic use
Spleen / pathology
Splenomegaly / complications*,  drug therapy,  pathology*
Sulfadoxine / therapeutic use
Time Factors
Travel
Chemical
Reg. No./Substance:
0/Antimalarials; 0/Drug Combinations; 130-95-0/Quinine; 2447-57-6/Sulfadoxine; 37338-39-9/sulfadoxine-pyrimethamine; 500-92-5/Chloroguanide; 58-14-0/Pyrimethamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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