Document Detail


Massive hepatomegaly: a presenting manifestation of multiple myeloma.
MedLine Citation:
PMID:  12696828     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a 50-year-old woman presenting with isolated massive hepatomegaly. Liver histology showed dilated sinusoids within which some atypical cells, probably of hematopoeitic origin, were identified. Bone marrow was densely packed with similar atypical cells with high nucleo-cytoplasmic ratio, which tested positive for plasma cell markers. Plasma protein electrophoresis showed a distinct M spike in the gamma globulin fraction and skeletal survey revealed multiple lytic lesions in the skull and pelvic bones. Thus, a final diagnosis of multiple myeloma was made. The patient has received six cycles of chemotherapy and is doing well.
Authors:
Anil Jain; P Chakraborty; Surinder Singh Rana; A Kundra; Rohit Goyal; K Das; S Anuradha; P Kar
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology     Volume:  22     ISSN:  0254-8860     ISO Abbreviation:  Indian J Gastroenterol     Publication Date:    2003 Mar-Apr
Date Detail:
Created Date:  2003-04-16     Completed Date:  2003-05-01     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8409436     Medline TA:  Indian J Gastroenterol     Country:  India    
Other Details:
Languages:  eng     Pagination:  62-4     Citation Subset:  IM    
Affiliation:
Department of Medicine, Maulana Azad Medical College, New Delhi 110 002.
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MeSH Terms
Descriptor/Qualifier:
Blood Protein Electrophoresis
Female
Hepatomegaly
Humans
Liver / pathology
Middle Aged
Multiple Myeloma / diagnosis*,  drug therapy,  pathology

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