Document Detail

Massive fetomaternal hemorrhage and fetal death: are they predictable?
MedLine Citation:
PMID:  10685227     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To report the incidence of massive fetomaternal hemorrhage (FMH) associated with fetal death and to test the hypothesis that FMH is more likely to occur in those with risk factors for FMH. STUDY DESIGN: All cases of fetal death of infants weighing > 500 gm between January 1, 1990 and December 31, 1994 were reviewed for evidence of massive FMH (> or = 2% fetal cells in the maternal circulation as measured by the Betke-Kleihauer test). Women with risk factors were compared with those without risk factors with respect to the occurrence of massive FMH. RESULTS: The prevalence of massive FMH was 14 of 319 (4.4%) cases, occurring in 4 of 102 (3.9%) of those with risk factors and 10 of 217 (4.6%) of patients without risk factors (p = 0.78). Otherwise unexplained fetal death was associated with massive FMH in 5 of 141 (3.5%). Major fetal anomalies were present in 5 of 14 (35.7%) cases of massive FMH. CONCLUSION: Clinical risk factors do not predict an increased likelihood of massive FMH. Massive FMH is associated with fetal anomalies. Betke-Kleihauer testing should be performed in all cases of fetal death, including those with anomalies regardless of the presence or absence of risk factors for FMH.
R Samadi; J S Greenspoon; I Gviazda; R H Settlage; T M Goodwin
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  19     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:    1999 Apr-May
Date Detail:
Created Date:  2000-03-09     Completed Date:  2000-03-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  227-9     Citation Subset:  IM    
University of Southern California School of Medicine, Department of OB/GYN, Los Angeles, USA.
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MeSH Terms
Fetal Death / epidemiology*
Fetomaternal Transfusion / epidemiology*
Maternal Age
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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