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Massive fetomaternal hemorrhage caused by an intraplacental choriocarcinoma: a case report.
MedLine Citation:
PMID:  20204132     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
Background. Intraplacental choriocarcinoma is a rare but highly malignant trophoblastic neoplasm. When found near term the risk of maternal metastasis is high because of the late diagnosis. Case. We describe a case of an intraplacental choriocarcinoma diagnosed postpartum after a near-term delivery of a severely anemic infant. A fetomaternal hemorrhage resulted in a hemoglobin concentration in the infant of only 2,1 g/dL. Neither mother nor child showed signs of metastatic disease. The macroscopic examination showed a hydropic placenta weighing more than 1 kilogram. Microscopy showed an intraplacental choriocarcinoma 3 cm in diameter. The tumor had infiltrated the maternal basal plate. Conclusion. Fetomaternal bleeding is a rare form of presentation of choriocarcinoma but its presence should always warrant detailed examination of placenta, mother, and infant.
Authors:
Anna-Karina Aaris Henningsen; Lisa Leth Maroun; Hanne Havsteen; Jens Svare
Publication Detail:
Type:  Journal Article     Date:  2010-03-03
Journal Detail:
Title:  Case reports in medicine     Volume:  2010     ISSN:  1687-9635     ISO Abbreviation:  Case Rep Med     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-05     Completed Date:  2011-07-14     Revised Date:  2013-02-21    
Medline Journal Info:
Nlm Unique ID:  101512910     Medline TA:  Case Rep Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  767218     Citation Subset:  -    
Affiliation:
Department of Obstetrics and Gynecology, Glostrup Hospital, University of Copenhagen, Nodre Ringvej 37, 2600 Glostrup, Denmark.
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