Document Detail


Massive cystic lymphangiomas of a fetus.
MedLine Citation:
PMID:  16359496     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We present a fetus with progressive massive subcutaneous lymphangiomas leading to intrauterine death. A 28-year-old woman was referred to our hospital because of a precordial cystic mass of the fetus. An ultrasound revealed lymphangiomas extending from bilateral axillae to the anterior chest wall. At 18 weeks' gestation, amniocentesis was performed and the karyotype of the fetus was found to be normal 46, XY. Thereafter the lesions increased in size gradually and spread over the body. Amniotic fluid decreased, pericardial, and pleural effusion appeared, and cardiomegaly became evident. The fetus died in utero at 25 weeks' gestation. Postmortem examination revealed a male fetus surrounded with multicystic soft masses spreading over the body, and syndactyly (left third and fourth fingers) was present. Histologically, a number of irregularly dilated lymphatics extended through subcutaneous tissues to the skeletal muscles. No communications between the cysts and the thoracic or abdominal cavity existed, and no lymphatic dilations in the viscera were confirmed. As far as we know, such conditions have rarely been reported. Considering that in previous literature, a favorable prognosis of a fetus with an atypically located (lateral cervical or non-cervical) lymphangioma with a normal karyotype has been reported, our case may be included in a distinct pathological entity. When we find a lymphangioma in a fetus, careful follow-up by ultrasound is mandatory.
Authors:
Akiko Hayashi; Akihiko Kikuchi; Yasuhiro Matsumoto; Mikiko Tatematsu; Tsuguhiro Horikoshi; Yoshifumi Ogiso; Nobuya Unno
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Congenital anomalies     Volume:  45     ISSN:  0914-3505     ISO Abbreviation:  -     Publication Date:  2005 Dec 
Date Detail:
Created Date:  2005-12-19     Completed Date:  2006-02-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9306292     Medline TA:  Congenit Anom (Kyoto)     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  154-6     Citation Subset:  IM    
Affiliation:
Department of Obstetrics, Center for Perinatal Medicine, Nagano Children's Hospital, Toyoshina, Nagano, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adult
Amniocentesis
Female
Fetal Death
Fetal Diseases / diagnosis*
Gestational Age
Humans
Infant, Newborn
Karyotyping
Lymphangioma / diagnosis*
Magnetic Resonance Imaging
Male
Pregnancy
Prenatal Diagnosis*
Subcutaneous Tissue
Ultrasonography, Prenatal

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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