Document Detail


Massive cranial osteolysis, skin changes, growth retardation and developmental delay: Gorham syndrome with systemic manifestations?
MedLine Citation:
PMID:  20186788     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report on a 16-month-old girl with multiple swellings on her skull due to massive osteolysis, growth retardation, facial anomalies, and wrinkly skin with mosaic hypopigmentation. She also had severe hypercalcemia, which gradually returned to normal levels. The condition likely represents Gorham syndrome with systemic manifestations.
Authors:
K M Girisha; H K Ganesh; Lakshmi Rao; P S Srilatha
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of medical genetics. Part A     Volume:  152A     ISSN:  1552-4833     ISO Abbreviation:  Am. J. Med. Genet. A     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-01     Completed Date:  2010-04-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101235741     Medline TA:  Am J Med Genet A     Country:  United States    
Other Details:
Languages:  eng     Pagination:  759-63     Citation Subset:  IM    
Copyright Information:
(c) 2010 Wiley-Liss, Inc.
Affiliation:
Department of Pediatrics, Kasturba Medical College, Manipal, Karnataka, India. girishkatta@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / genetics*
Developmental Disabilities / genetics*
Female
Growth Disorders / genetics*
Humans
Hypopigmentation / genetics
Infant
Osteolysis, Essential / genetics*,  pathology*
Skin Abnormalities / genetics,  pathology
Skull / pathology*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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