| Mass spectrometry-based proteomics and its potential use in haematological research. | |
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MedLine Citation:
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PMID: 19916740 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In the last decade proteomics has made great progress reaching throughput and comprehensiveness comparable to genomics technologies. Mass spectrometry plays a key role in proteomics and has become an indispensable method for molecular and cellular biology because many cellular changes in response to internal or external stimuli can only be detected at the proteome level. Furthermore, different from genomics which depends on the availability of DNA or RNA, proteomics is not restricted to cellular samples, but also allows the analysis of biological fluids like serum, plasma or urine. This article provides an overview of the recent developments in proteomics techniques useful for haematological research. |
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Authors:
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Julia Fr?bel; Stefan Lehr; Rainer Haas; Akos Czibere |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Archives of physiology and biochemistry Volume: 115 ISSN: 1744-4160 ISO Abbreviation: Arch. Physiol. Biochem. Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2009-12-16 Completed Date: 2010-02-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9510153 Medline TA: Arch Physiol Biochem Country: England |
Other Details:
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Languages: eng Pagination: 286-97 Citation Subset: IM |
Affiliation:
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Department of Haematology, Oncology and Clinical Immunology, Heinrich-Heine-University, Moorenstrasse 5, D?sseldorf, Germany. julia.froebel@med.uni-duesseldorf.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Genomics / methods Hematology / methods Humans Mass Spectrometry / methods* Proteins / chemistry Proteome / chemistry Proteomics / methods* |
| Chemical | |
Reg. No./Substance:
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0/Proteins; 0/Proteome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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