Document Detail


Mass spectrometry of 1,3- and 1,5-dicaffeoylquinic acids.
MedLine Citation:
PMID:  15103652     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Samples of 1,3- (1) and 1,5-dicaffeoylquinic acid (2) and their hexaacetate derivatives were examined using positive and negative electrospray ionization mass spectrometry and tandem mass spectrometry. Differences in the various spectra allow the discrimination of each of the isomers. Specific losses in the spectra of 2 also permit the identification of the site of substitution of one of the caffeic acid moieties as being at the 5-position. The spectra of 3,5- (3) and 4,5-dicaffeoylquinic (4) acids and their hexaacetate derivatives were compared with those of 1 and 2 and their derivatives, and differences in ion abundances or the presence/absence of specific ions can be used to identify uniquely each of the compounds.
Authors:
Karl Schram; Petra Miketova; Jiri Slanina; Otakar Humpa; Eva Taborska
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of mass spectrometry : JMS     Volume:  39     ISSN:  1076-5174     ISO Abbreviation:  J Mass Spectrom     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-04-22     Completed Date:  2004-07-21     Revised Date:  2009-10-08    
Medline Journal Info:
Nlm Unique ID:  9504818     Medline TA:  J Mass Spectrom     Country:  England    
Other Details:
Languages:  eng     Pagination:  384-95     Citation Subset:  IM    
Copyright Information:
Copyright 2004 John Wiley & Sons, Ltd.
Affiliation:
Department of Pharmacology/Toxicology, Division of Medicinal and Natural Products Chemistry, College of Pharmacy, University of Arizona, Tucson, Arizona 85721, USA. Schram@pharmacy.arizona.edu
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MeSH Terms
Descriptor/Qualifier:
Cinnamates / analysis*,  chemistry*
Magnetic Resonance Spectroscopy
Mass Spectrometry / methods*
Molecular Conformation
Quinic Acid / analogs & derivatives,  analysis*,  chemistry*
Spectrometry, Mass, Electrospray Ionization / methods
Chemical
Reg. No./Substance:
0/1,3-dicaffeoylquinic acid; 0/Cinnamates; 1884-23-7/cynarine; 77-95-2/Quinic Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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